| Bioactivity | [Asp5]-Oxytocin acetate is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity. [Asp5]-Oxytocin acetate causes uterine contractions in vitro, enhanced by Mg2+. [Asp5]-Oxytocin acetate has the ability of rat uteroconstrictor, avian vasodilator, and rat antidiuretic[1]. | ||||||
| Invitro | [Asp5]-Oxytocin acetate 不仅对子宫张力受体具有高亲和力，而且具有与催产素相同的内在活性[1]。[Asp5]-Oxytocin acetate 对子宫的收缩作用可被 1 mM Mg2+ 增强[1]。[Asp5]-Oxytocin acetate 分别发挥与 20.3、41 和 0.14 单位/毫克的剂量的大鼠子宫扩张、禽血管抑制剂和大鼠抗利尿剂相同的作用[1]。 | ||||||
| Name | [Asp5]-Oxytocin acetate | ||||||
| Sequence | Cys-Tyr-Ile-Gln-Asp-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge:Cys1-Cys6) | ||||||
| Shortening | CYIQDCPLG-NH2 (Disulfide bridge:Cys1-Cys6) | ||||||
| Formula | C45H69N11O15S2 | ||||||
| Molar Mass | 1068.22 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
[Asp5]-Oxytocin acetate
CAS: F: C45H69N11O15S2 W: 1068.22
-Oxytocin acetate is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity.
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